Wednesday, February 25, 2009

Impotence Drug: Viagra Viagra

Composition and role of the principle of
1.ViagraSildenafil citrate are just in March 27, 1998 the United States Food and Drug Administration (FDA) approved the listing of prescription drugs, must be used by a physician's prescription. Is the first FDA approved a treatment for impotence drugs.
The chemical composition of 2.Viagra for: 1 - [[3 - (6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo [4,3-d] pyrimidin-5-yl) -- 4-ethoxyphenyl] sulfonyl]-4-methylpiperazine citrate.
3.Viagra the role of Principle: When sexual excitement when, Viagra in the corpus cavernosum penis generated Nitric oxide, referred to as NO, NO could activate guanylate cyclase, thus increasing cyclic guanosine monophosphate (referred to as cGMP) for selecting, cGMP can intracavernous relaxation of smooth muscle, smooth muscle relaxation First, a large number of blood will be injected into corpus cavernosum of erectile.
Effect
1.Viagra after oral administration, was quickly absorbed in the blood concentration of 60 minutes on the highest point, can last four hours, 2 hours later, performance started to decrease, therefore, taking the best time, are having sex one hour before. But 30-4 minutes before using it, is still an acceptable range.
2.Viagra of any reasons for impotence are valid, the so-called impotence, refers to the penis when sexual excitement could not erectile. Whether it is psychological impotence, or erectile dysfunction caused by disease, have a therapeutic effect, such as diabetes, high blood pressure, spinal injury , prostate surgery, and unknown causes of impotence. their effects are more than 60%.
Who should not take viagra?
1. Child
2. Are taking Containing Nitrates (such as: nitroglycerin-a coronary artery expansion agent) and other drugs. A combination of viagra and nitrates may cause a rapid decline in blood pressure, but also in sexual intercourse at that time, increase the heart load, if the rapid decline in blood pressure, may be lethal.
3. Women: FDA temporarily prohibited for women, but some medical institutions have begun to trial in women, according to the rationale for study of drug response, similar male penis, Viagra can also make it more sensitive and congestive. Should be able to make women more vulnerable to climax, so the near future, perhaps some women can also be used to do a Viagra treatment.
How to use?
There are three agents: 25mg, 50mg, 100mg, in general are from 50mg to start, can only be taken once a day each in 30 minutes before sexual activity to be taken four hours, preferably 1 hour ago. To rely on their individual response to different , the dose can be increased to 100mg or 25mg.
Taking those matters to the attention?
A: do a good job before taking a medical examination and consult their physician to identify the causes of impotence.
B: Some of anemia, leukemia, multiple myeloma, or abnormal penile shape of people taking viagra, it may lead to persistent erection (Priapism) while using this drug is not recommended.
C: What position should reduce the amount of drugs: (1). Older people over the age of 65, poor kidney function, liver cirrhosis or other liver disease, because blood viagra slower excretion, blood concentrations increased, so reduction must be taken. (b) are taking Cimetidine, Erythromycin, Itraconazole, Ketoconazole and other drugs, the reduction should take
D: and other impotence drugs is not clear whether the combination, therefore, is not recommended while taking.
Side effects
If you control the use of not more than twice a week, each no more than 100mg, side effects are quite low. Not satisfied with the drug use of people give up, only 2.5%.
The role include: headache, facial flushing, gastrointestinal discomfort, stuffy nose, diarrhea, fear of light, a temporary visual impairment, such as blue-green to distinguish unclear.
Conclusion
According to statistics, the United States has 30 million men, suffer from some degree of impotence (Impotence or Erectile dysfunction), if the same ratio to the population count, Taiwan, about three million men have a similar problem, viagra birth, will be for these people has brought great confidence.
Notes
1: aged between 40-55 years old men, if have not the problem of impotence, but now it has to use Viagra, Please note that cardiovascular examination, because of his impotence, is very likely that the potential cardiovascular disease symptoms of an advance.
2: From the FDA has approved the listing at the end of July 1998, the United States 35000000 Viagra already left for the hospital, and can be described as unprecedented, but in 69 cases have died after taking the report, therefore, the American Heart Association and American Heart Association August 10 warned that the following three conditions, taking Viagra should be particularly cautious with: 1. Although there were no prior taking nitrate drugs, but in taking Viagra after myocardial infarction, at this time if taking nitrate drugs, may still be fatal, 2 . hyperemia and hypotension in patients with heart disease, 3. to multiple drug treatment of hypertensive persons.
69 deaths, the average age is 64 years old, therefore, over 60 years old and has cardiovascular problem, and taking Viagra, they should be particularly cautious.

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